Prof. Bikash Medhi
Designation : Professor


 :: Contact Details
  Phone No.    :   9914207510
  Ext No.        :   5250
 :: Educational Qualification
  Graduation :   MBBS from Assam Medical College Dibrugarh in year 1992
  Post Graduation :   MD from AIIMS New Delhi in year 1997
 :: Area of Interest
       Area Of Interest       :
1. Experimental Pharmacology
2. Molecular Pharmacology
3. Clinical Trials
4. Autism and Epilepsy

 :: Research & Projects
      Extramural Projects       :
 S. No
Project Title

1.     Combined effects of G-CSF and dizocilpine(MK-801) on acute phase changes induced by partial global cerebral ischemia inmice.

2.     Study to evaluate correlation of differenttype of peripheral inflammation and epilepsy and role of cytokines ininflammation induced in experimental model in rats.

3.     Effect of Metformin on Alzheimer’s Disease inrats.

4.     Development of ophthalmic formulations ofacetazolamide and memantine using novel drug delivery techniques for thetreatment of glaucoma.

5.     Comparative Evaluation of Thalidomiode,Sulfasalazine with Nanotechnology Based Drug Delivery in Experimentally InducedInflammatory Bowel Disease in Rats.

      Departmental / P.G.I.
  Past Events:

4-6th December, 2015

Upcoming Events:

20-23rd October, 2016

Registration Form
General Information & Registration fee
Other Details

      Research In
Dr. Bikash Medhi
Dr. Bikash Medhi

Department of Pharmacology
PGIMER, Chandigarh
Coordinator, PGIMER Pharmacovigilance Centre, Chandigarh.

Ex-Secretary, Clinical Pharmacology of  Indian Pharmacology Society.

Research Block B, 4th Floor, Room no 4043,
Postgraduate Institute of Medical Education & Research, Chandigarh, 160012, India

Mobile: +91-9914207510

 Neurobehavioral Research Laboratory (NBRL) & Experimental Pharmacology Laboratory (EPL)

Our Team:
The Neurobehavioral Research Laboratory (NBRL), Experimental Pharmacology Laboratory (EPL)  and Pharmacovigilance Center  is composed of a multi-disciplinary team of researchers.
The following sections provide detailed information about each of the individual team members.


Dr. Ajay Prakash (Senior Demonstrator)

Ph.D., Panjab University, Chandigarh


Contact: +91-9781119969

Area of Research: Neuroscience, Clinical Pharmacology & Pharmacovigilance.

Rakesh Kr Ruhela (PhD Student)

M.Sc., Molecular Biology & Biotechnology (MBBT), Tezpur University, Assam


Contact: +91-9814564145

Area of Research: Autism, Cognitive Neuroscience & Epilepsy

Baldeep Kumar (PhD Student)

M.Pharmacy, Drug Discovery& Drug Development, Panjab University, Chandigarh.


Contact: +91-8194896278

Area of Research: Neurosciences, Epilepsy, Stroke, Pharmacokineticand Pharmacodynamic Studies.

Harjeet Kaur (PhD Student)

M.Sc., PharmaceuticalChemistry, Panjab University, Chandigarh.


Contact:  +91-9914527459

Area of Research: Neurosciences, Stroke, Epilepsy, Herbal Medicines, Nano Medicines.


Shweta Sinha (PhD Student)

M.Sc. Medical Biotechnology, Sardar Patel University, Gujarat

Contact: +91-8437503897     

Area of Research: Drug Resistant and Cerebral Malaria and its Immunological basis, Antimalarials drug discovery.                                            


D.Hari Krishna Reddy (PhD Student)

M.Pharma.,Pharmacology, Sri Venkateswara University, Tirupati (A.P) & Central Drug Research Institute (CDRI), Lucknow (U.P)


Contact: +91-8725984535
Area of Research: Cerebral Stroke, Stem Cells and Neurodegenerative diseases


Rahul Singh (PhD Student)

M.Sc. PharmaceuticalChemistry, Punjabi University, Patiala


Contact: +91-9988180587

Area of Research: Celiac disease-Preclinical study, Non-dietary approaches, Immunological aspects 


Harish Kumar (Ph.D. Scholar)

M.Sc. Pharmacology, PGIMER,Chandigarh


Contact: +91-8901009946

Research Area. Ocular Pharmacology (Glaucoma), Neuropharmacology (Neurodegenerativedisease, Alzheimer’s disease), Gastro-intestinal pharmacology (IBD)


Nitika Garg (PhD Student)

M.Sc.Hons. School of Biochemistry, Panjab University (PU)


Contact: +91-8427866210

Area of Research: Refractory epilepsy

ShammyChandel (Ph.D Student)

M.Sc.(Hons.) Microbiologyfrom H.P. University, SummerHill, Shimla Himachal Pradesh


Contact: +91-9888769087

Area of Research:Epileptogenesis, Traumatic Brain Injury,Alzheimer’s disease, Neurodegenerative disease, IBD and Colon Cancer.


Dr.Missamma M. (MD Student)

MBBS from ASRAM MedicalCollege, Eluru


Contact: +91-7529878585

Area of Research:  Neurodegenerative Diseases


Shringika Soni (JRF)

M.Tech., Cognitive Neurosciences, Rajasthan University, Jaipur, Rajasthan.


Contact: +91-9592912925

Area of Research: Nano medicines, Stem cells & Autism.

Ashutosh Singh (JRF)

M.Sc. PharmaceuticalChemistry, Punjabi University, Patiala


Contact: +91-9653511424

Research Area: Alzheimer's and Dementia, Cerebral Malaria


Dr. Phulen Sarma (DM Student)



Contact: +91-8728830834

Area of Research:  Neurosciences, Pharmacogenomics


Eshani mahajan (M.Sc. Student) (Panjab University)


Contact no.:-7508283825

Lab Alumni


Dr. Pooja Sarotra  (Clinical Research Associate)

Ph.D., Panjab University, Chandigarh


Contact: +91-9815273784

Area of Research: cancer biology, Clinical Research


Dr. Rakesh Sewal

Ph.D., PGIMER, Chandigarh



Area of Research: Epilepsy

Neurobehavioural Research Laboratory (NBRL):

As part of the PGIMER, NBRL provides a preclinicaldiscovery platform for CNS target validation in preclinical in vivo and invitro models. Our well validated neurobehavioral assessment tools in CNSdisease models provide a unique platform for the screening and profiling ofexperimental therapeutics and genetic rodent models. We aim to accelerate theprogress in both fundamental and applied studies of nervous system function. Ouroverarching goal is to lead and enable translation of scientific discoveriesinto novel therapeutic approaches that improve the quality of life for patientswith disorders of the brain and spinal cord.  Our disease models focusincludes: cognition and memory, Autism Spectrum Disorder, Alzheimer’s disease, ALS,and Schizophrenia, as well as social interaction.


Abhishek Misra (PhD Student)

M.Pharmacy, NIPER, Guwahati


Contact: +91-7508163275

Area of Research: Autism, Stem cells

Name of specialized lab

Name of equipment

Description of function


Ethovision XT 11.5

Video-tracking software used for various behavioural tests


Cognitive (learning/memory) tests

Barnes maze, Morris water maze, novel object recognition, passive avoidance,  T-maze, Y-maze


Depression/anxiety tests

Elevated plus maze, light-dark boxes, novelty suppressed feeding, open field, Porsolt forced swim, sucrose preference, tail suspension


Motor/sensorimotor tests

Adhesive removal, beam break, cylinder, grip strength,home-cage locomotor activity, pole test, rotarod, rotational behaviour, staircase,


Olfactory tests

Buried food, habituation-dishabituation, odour discrimination, odour preference


Social tests

Social interaction (adult and juvenile), social defeat, sociability cage,


Experimental Pharmacology Laboratory (EPL):

Pharmacovigilance Center:

Pharmacovigilance, as defined by the World Health Organization, is the science and activities relating to the detection, assessment, understanding and prevention of adverse events or any other possible drug-related problems. Recent inclusions to this definition are: herbals, traditional and complementary medicines, blood products, biological, medical devices and vaccines. For further details please visit

Working of Pharmacovigilance

If there is any suspicion that an adverse event or adverse reaction has occurred, the healthcare professional attending to the patient, can fill up the suspected ADR former patient suspects that he has experienced an ADR can report  to the nearest ADR Monitoring Centers (AMCs) under Pharmacovigilance Programme of India (PvPI). There is a prescribed form that can be used in making reports to AMCs which can be downloaded from the website of IPC  The details of IPC are given in the website of IPC i.e.  The ADRs will be sent to WHO-Uppsala Monitoring Center (UMC) for analysis and signal detection.  Simultaneously ADRs are evaluated at NCC and the inferences are used to recommend regulatory body i.e. CDSCO to take  necessary regulatory interventions, besides communicating risks to healthcare professionals and the public.

Regional Resource and Training& Technical Support Center for North India. (AMC-PGIMER)

PGIMER Chandigarh was identified as ADR Monitoring Centre (AMC) in July 2010. Dr. Bikash Medhi was appointed as Coordinator right from the first phase of Pharmacovigilance Program of India. PGIMER Chandigarh was later identified by National Coordinating Center as Regional Resource and Training& Technical Support Center for North India. Apart from the collection of ICSR’s; AMC has been actively involved in creating awareness amongst the health careprofessionals by means of organizing different CME’s throughout the Northern India.

Working of AMC-PGIMER

  • Collection of ADR reports from hospital of PGIMER, Chandigarh.
  • Reviewing  the ICSR’s for seriousness and expectedness.
  • Checking the completeness of reports for quality followed by causality assessment of ADR/AE cases, Follow up with the reporter for any incomplete information.
  • Entry of ADR reports into Vigiflow (WHO’s database) by using inbuilt WHO-ART, ICD10, WHO drug dictionary.
  • Delivering lecture on trending news and issues on drug safety, importance of reporting the ADR’s; for sensitization of healthcare professionals (Doctors, Nurses,Pharmacists).
  • Preparing the monthly report of the ADR monitoring center.
  • Documentation  and archival of the ADR reports in both soft and hard copies.
  • Providing training to the personnel under pharmacovigilance program of India in north  India on “Vigiflow, reporting form, SOP’s”.

Pharmacovigilance Team:


Mr. Vikas Kumar (Technical Associate)

M. Pharm.(Pharmacology), Uttarakhand Technical University, Dehradun, Uttarakhand


Contact: +91-987-637-2607

Area ofExpertise/Skills: Pharmacovigilance,VigiFlow, WHO-ART, ICD-10, ICSR processing, MedDRA, ICH Guidelines, MedicalCoding, Medical Writing, Epidemiology, Public Health, Pharmacogenomics,Pharmacogenetics.


Dr. PrashantChandra Fuloria, (Technical Associate)

Doctor OfPharmacy (PharmD), Sri Adi Chunchanagiri College of Pharmacy (Rajiv GandhiUniversity of Health Sciences) Bangalore, Karnataka



Area of Research: Adverse drug reaction reporting,Vigiflow processing, WHO ICD-10 coding,ICSR review and Causality assessmentetc.

Photo Gallery:

      Area Of

1. Cognitive Neurosciences
2. Autism
3. Epilepsy
4. Pharmacogenomics & Pharmacoproteomics
6. Pharmacovigilance

      Future Plans       :
      Awards & Honours       :
  1. Awarded Dr. D N Prasad memorial award with Goldmedal 2009 from Indian Council of Medical Research (ICMR), New Delhi.
  2. Dr V K Bhargava Award with Gold medal  from National Academy of Medical Sciences 2013
  3. Col. R N Chopra Oration 2014 by Indian Pharmacology Society(IPS)
  4. Awarded Dr.B N. Ghosh Oration at 43rd Annual Conference of IPS andInternational Conference on “Pharmacology & Translational Research” will beorganized by National Executive Committee in association with Food and DrugToxicology Research Centre, National Institute of Nutrition, Hyderabad from13th – 16th December, 2010.
  5. Awarded International Fellowship from Alzheimer's Association International Organization(AAIC), July 18-22, 2015 at the Washington DC, USA  
  6. Awarded International Fellowship from Alzheimer's Association International Organization(AAIC), July 13-18, 2013 at the Boston,USA. 
  7. Awarded Bharat Joti Award 2013
  8. Awarded Best 2nd Prize for paperen titled: Effects of artemisinin, artemether, arteether on the pharmacokineticsof Phenytoin. In InternationalComprehensive Update on Diagnostic and Therapeutic in Epilepsy andNeuro-Electrophysiology Workshop (CUTE conference), New Delhi, Feb4&5,2006.
  9. Member of Investigational New Drug ( INDcommittee, DCGI office, Ministry of Health, Nirman Bhawan, Government of India.
  10. Secretary Clinical Pharmacology of  Indian Pharmacology Society
  11. Selected as Core panel of expert for Task Forceto frame guidelines for submission of dossiers or proposals for regulation of biotechproducts (r-D~A product),Govtof India, Govt of India, Ministry of Health and Family Welfare, Nirman Bhawan,New Delhi, 2011
  12. Core member of Expert committee CompensationGuideline Govt of India, Govt of India, Ministry of Health and Family Welfare,Nirman Bhawan, New Delhi, 2011
  13. Elected as Fellow of International Medical SciencesAcademy(FIMSA) in 2006
  14. Awarded Member of National Medical Academy (MAMS) 2009
  15. Elected for National advisory board member in JKscience, Journal of Medical Education and research.
  16. Elected for Editorial Board member, World Journal ofGastroenterology (2010-2012)
  17. Elected as Editorial Board for  Journal of Neuroscience and Behavioral Health
  18. Executive committee member of Society for Rational DrugUse, India
  19. Travel grant from Department of Science and Technologyto attend IMSACON at Clare college in July 2002, Cambridge University, UK.
  20. Travel grant from Department of Science and Technologyto attend IMSACON at Mayo Clinic  in 9-11th  July 2002, Rochester, Minnesota, USA
  21. Travel grant from Indian National Sciences Academy toattend International Challenges in Pediatric Pharmacology, Satellite Symposium(15th World Congress of Pharmacology) Shanghai, China   June 28 – 30, 2006
  22. Investigator award from International Epilepsy Society,Dublin, Ireland,   to attend EpilepsyCongress at Singapore, 7-12th July 2007.
  23. Travel award from CSIR 2008 to attend EpillesyCongress, Berlin, Germany
  24. Travel award from DST 2008 to attend ExperimentalBiology, Washington DC,USA
  25. Travel award from UGC 2008
  26. Travel award from UGC 2009, to attend Experimental Biology,New Oreland,USA
  27. Trained by DST  as GLP inspector 2010
  28. Trained by USA-FDA  as GCP inspector 2008-2010
  29. Executive committee member of Society forRational Drug Use, India
  30. Executive committee member of Society forPharmacovigilance, India
  31. Epilepsy award, Manila from ILAE March 2012.
      Member Of Professional
1. Life member of Indian pharmacological Society (IPS)
2. Life member of Association of Physiologist & Pharmacologist of Indian (APPI)
3. Life member of Pharmacovigillance society of India (PSI)
4. Life member of International Society for chemotherapy
5. International Medical Sciences Academy
 :: Publications(In Vancouver Style)

Practical Manual ofExperimental and Clinical Pharmacology, JP Brothers Publication, New Delhi


Advance Pharmacology  by Bikash Medhi & Ajay Prakash Publishers:B S Publication, Hyderabad Ist Edition,2014